Based on the information available, Vascepa (icosapent ethyl) can generally be taken safely with other medications, but it is crucial to consult with a healthcare provider or pharmacist before starting any new medication, including Vascepa, to ensure there are no potential drug interactions [1].

Icosapent ethyl, the active ingredient in Vascepa, is an ester of the omega-3 fatty acid, eicosapentaenoic acid (EPA) [1]. It is primarily used to reduce triglyceride levels in adults with severe (≥500 mg/dL) hypertriglyceridemia [1].

According to the prescribing information for Vascepa, there are no specific contraindications regarding the co-administration of Vascepa with other medications [1]. However, it is essential to consider that Vascepa can potentially increase the bleeding risk when taken with other medications that also increase the risk of bleeding, such as anticoagulants or antiplatelet agents [1].

In summary, while Vascepa can generally be taken safely with other medications, consulting a healthcare provider or pharmacist before starting any new medication is always recommended to ensure there are no potential drug interactions or increased risks of adverse effects.

Sources:
[1] Vascepa (icosapent ethyl) capsules, for oral use. Full Prescribing Information. Amarin Pharma Inc. June 2021. <https://www.vascepa.com/sites/default/files/Vascepa-PI-2021-06-23.pdf>