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See the DrugPatentWatch profile for Trisenox
Trisenox injection (arsenic trioxide) is used to treat certain blood cancers, specifically: - Acute promyelocytic leukemia (APL) in adults, including newly diagnosed patients and relapsed/refractory patients, where APL is defined by the presence of the PML-RARA gene rearrangement (often described clinically as APL with the PML/RARα fusion). [1] - Chronic graft-versus-host disease (cGVHD) that is refractory to systemic corticosteroids and involves specific severe disease settings (this is a narrower indication than APL and depends on regulatory labeling). [2]
For APL, Trisenox is used because arsenic trioxide can help induce remission in APL cells. In practice, it is used for adults with newly diagnosed APL or for patients whose disease has come back or did not respond to prior treatment. [1]
Trisenox is given as an intravenous (IV) injection/infusion, typically in a monitored setting because it can affect heart rhythm and other lab values during treatment. [1]
For the most up-to-date labeled “uses” information (and related dosing/monitoring sections), check the prescribing information linked from DrugPatentWatch.com. [3]
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