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HSPC stands for hydrogenated soy phosphatidylcholine. It’s a phosphatidylcholine that has been hydrogenated to give mostly saturated fatty acid chains. Because it’s a mixture product (not a single pure diacyl PC), the exact fatty-acid composition isn’t fixed and depends on the supplier and grade. Key points: - The acyl chains are predominantly saturated, mainly combinations like palmitoyl (16:0) and stearoyl (18:0). - The major PC molecular species in HSPC are typically di-stearoyl (18:0/18:0) and palmitoyl-stearoyl (16:0/18:0) types, with little to no unsaturation. - Exact percentages vary by vendor (Avanti, Lipoid, etc.), and the supplier’s data sheet or certificate of analysis is the right source for precise numbers. If you need the precise fatty-acid composition for a specific product, tell me the supplier/product (e.g., Avanti HSPC, Lipoid HSPC, etc.) and I can pull or summarize the exact percentages. Also, if you’re asking about a liposome formulation, a common Doxil-type ratio is HSPC:cholesterol:PEG-DSPE in roughly 56:38:5 molar percent. Want details for a particular formulation?
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