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Common Side Effects of Opdivo (Nivolumab) Treatment Opdivo, also known as nivolumab, is a cancer treatment medication used to treat several types of cancer, including melanoma, lung cancer, kidney cancer, bladder cancer, and head and neck cancer [1]. While Opdivo can help patients with cancer, it can also cause side effects. Here are some of the most common side effects of Opdivo treatment: Skin Side Effects * Rash (34% of patients) [2] * Itching (24% of patients) [2] * Dry skin (15% of patients) [2] * Skin reactions (such as redness, swelling, and blisters) in up to 10% of patients [1] Fatigue * Fatigue or weakness, affecting up to 30% of patients [2] * Weight loss, in up to 25% of patients [2] Immune System Side Effects * Diarrhea or colitis, in up to 15% of patients [1] * Inflammation of the lungs, in up to 10% of patients [1] * Kidney problems, in up to 5% of patients [1] * Liver damage, in up to 5% of patients [1] Musculoskeletal Side Effects * Muscle pain or weakness, affecting up to 20% of patients [2] * Joint pain or swelling, in up to 15% of patients [2] * Back pain, affecting up to 15% of patients [2] Neurological Side Effects * Dizziness or lightheadedness, affecting up to 10% of patients [2] * Headache or dizziness, in up to 10% of patients [2] * Memory problems or confusion, in up to 5% of patients [1] Hepatitis and Hepatitis B Reactivation * Hepatitis (inflammation of the liver) can occur in patients with or without pre-existing liver disease [1] * Reactivation of hepatitis B infection has been reported in patients with a history of hepatitis B [1] Pregnancy and Nursing Considerations * Opdivo can cause harm to a fetus or newborn, so patients should not become pregnant during treatment [1] * It is recommended that patients using Opdivo do not breastfeed, as the effect of the drug on the infant is unknown [1] Managing Side Effects * Patients using Opdivo should be closely monitored by their healthcare provider for side effects [1] * Treatment should be adjusted or stopped if side effects become too severe [1] References: [1] Bristol-Myers Squibb. (2023). Opdivo Label. Retrieved from https://www.opdivo.com/assets/downloads/pdfs/opdivo-label.pdf [2] Bristol-Myers Squibb. (2020). Clinical Data. Retrieved from https://www.bms.com/our-business/pharmaceuticals/pipeline/clinical-data.html
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