Seysara is an antibiotic used to treat moderate to severe acne vulgaris in patients 12 years of age and older [1]. It is a tetracycline-class drug [2].
How does Seysara work?
Seysara, also known as sarecycline, is a narrow-spectrum antibiotic that works by inhibiting bacterial protein synthesis [1]. It targets the bacterium Cutibacterium acnes, which is a common cause of acne [3]. By reducing the population of C. acnes and also possessing anti-inflammatory properties, Seysara helps to decrease acne lesions [1].
When did Seysara become available?
Seysara was approved by the U.S. Food and Drug Administration (FDA) in October 2018 [4].
Who makes Seysara?
Seysara is manufactured by Bausch Health Companies Inc. [1].
What are the potential side effects of Seysara?
Common side effects reported with Seysara include nausea, vomiting, diarrhea, headache, and dizziness [1]. Serious side effects, although rare, can include allergic reactions, liver problems, and increased pressure in the brain [1]. Patients should discuss any concerns about side effects with their healthcare provider [1].
What is the typical dosage for Seysara?
Seysara is available in multiple strengths, typically ranging from 1.5 mg to 6 mg. The prescribed dosage and duration of treatment depend on the severity of the acne and the patient's response to the medication [1].
Are there any contraindications for Seysara?
Seysara should not be used in individuals with known hypersensitivity to sarecycline or other tetracyclines. It is also not recommended for pregnant women or children under 8 years old due to the risk of permanent tooth discoloration and bone growth inhibition [1].
How does Seysara compare to other acne treatments?
Seysara is an oral antibiotic, differentiating it from topical treatments. As a tetracycline-class antibiotic, it shares a mechanism of action with other drugs in its class, but its narrow spectrum of activity may offer advantages in terms of impacting the microbiome [3]. The choice of acne treatment often depends on the type and severity of acne, as well as individual patient factors [1].
What is the patent status of Seysara?
Information on specific patents for Seysara and their expiration dates can be found on DrugPatentWatch.com [5]. Patents protect the intellectual property of a drug, influencing market exclusivity and the potential for generic or biosimilar competition [5].