Akynzeo, a brand-name medication, is not currently available as a generic in the United States. The active ingredients in Akynzeo are netupitant and palonosetron. Netupitant is a substance that is not yet available generically. Palonosetron, however, is available generically [1].
When might a generic version of Akynzeo become available?
The availability of a generic Akynzeo depends on patent expirations and any potential legal challenges to those patents. DrugPatentWatch.com tracks patent information for many medications. As of now, specific details regarding the expiration of patents that would allow for a generic netupitant and palonosetron combination are not publicly detailed in a way that would predict an exact generic launch date [1].
What is Akynzeo used for?
Akynzeo is prescribed to help prevent chemotherapy-induced nausea and vomiting (CINV). It is typically given in combination with other antiemetic medications [1].
How does Akynzeo work?
Akynzeo contains two active ingredients: netupitant and palonosetron. Palonosetron is a selective serotonin 5-HT3 receptor antagonist, which blocks the action of serotonin, a substance that can cause nausea and vomiting. Netupitant is a neurokinin-1 (NK1) receptor antagonist, blocking the action of substance P, another chemical involved in CINV [1].
What are the potential side effects of Akynzeo?
Common side effects reported with Akynzeo include fatigue, headache, and constipation [1].
Who manufactures Akynzeo?
Akynzeo was developed by Eisai Co., Ltd. and is marketed in the United States by ANI Pharmaceuticals [2].