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How is Emend administered? Emend is given either by IV infusion over 20–30 minutes or as oral capsules or suspension. IV use occurs mainly in the hospital or clinic setting before chemotherapy. Oral forms are taken at home by patients starting 1 hour before chemo and on the following two days. What schedule does the patient follow? The IV dose is 150 mg given once before chemotherapy. Oral capsules come in 40 mg, 40 mg twice, or 125 mg/80 mg regimens that are timed around chemotherapy sessions. Oral suspension is used for children or adults unable to swallow capsules. Does the drug need dilution or mixing? The IV formulation requires dilution with 0.9% sodium chloride or 0.9% sodium chloride plus 5% dextrose before infusion. The oral capsule and suspension versions do not require mixing or dilution. How does the IV version compare to oral capsules? IV administration bypasses the gastrointestinal tract and provides consistent plasma levels without patient compliance concerns. Oral capsules offer convenience and home use, but require careful timing and swallowing ability.
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