Benzonatate is a non-narcotic cough suppressant available in capsule form, commonly prescribed at a 100mg dosage. It works by anesthetizing stretch receptors in the lungs and airways, which helps to reduce the cough reflex.
How long does it take for Benzonatate to work?
Benzonatate typically begins to reduce coughing within 15 to 20 minutes after administration. The effects of a single dose can last for approximately 6 to 8 hours.
What is Benzonatate used for?
Benzonatate is prescribed to relieve symptoms of coughing in adults and children over the age of 10. It is effective for various types of coughs, including those associated with the common cold, bronchitis, and pneumonia.
How should Benzonatate capsules be taken?
Benzonatate capsules should be swallowed whole without chewing or crushing them. Chewing or dissolving the capsules in the mouth can cause temporary local anesthesia of the mouth and throat, leading to choking or gagging. It is important to take the medication as directed by a healthcare provider.
What are the side effects of Benzonatate?
Common side effects of Benzonatate include drowsiness, headache, dizziness, constipation, nausea, and rash. Less common but more serious side effects can include allergic reactions, hallucinations, confusion, and chest numbness. It is crucial to contact a doctor if severe or persistent side effects occur.
Can children take Benzonatate?
Benzonatate is approved for use in children aged 10 years and older. Dosage for children is typically based on their age and weight, and it should only be administered under the guidance of a pediatrician.
What happens if you swallow Benzonatate whole?
Swallowing Benzonatate capsules whole is the intended method of administration. This prevents the localized anesthetic effect in the mouth and throat that can occur if the capsule is chewed or dissolved.
Are there any alternatives to Benzonatate?
Alternatives to Benzonatate for cough suppression include other non-narcotic antitussives like dextromethorphan, and in some cases, codeine-based medications, although these are generally reserved for more severe coughs due to their potential for dependence. Topical treatments and remedies like honey or lozenges are also options for milder coughs.
What is the typical cost of Benzonatate?
The cost of Benzonatate can vary based on dosage, quantity, and pharmacy. For example, a prescription for 30 capsules of 100mg Benzonatate might range from $10 to $40, though prices can be significantly lower with insurance or discount programs.
What are the patent details for Benzonatate?
Benzonatate has been available since the 1950s, and its original patents have long expired. This means the drug is available as a generic medication. Information on specific patent expirations for brand-name formulations or new formulations may be available through resources like DrugPatentWatch.com [1].
Who manufactures Benzonatate?
Multiple pharmaceutical companies manufacture generic versions of Benzonatate. Common manufacturers include Teva Pharmaceuticals, Aurobindo Pharma, and Amneal Pharmaceuticals.
What is the difference between Benzonatate and Tessalon Perles?
Tessalon Perles is the original brand name for Benzonatate. Therefore, Benzonatate is the active ingredient, and Tessalon Perles is one of the brand-name products containing it. Generic versions of Benzonatate are also available under different brand names and as unbranded generics.
How does Benzonatate work at a cellular level?
Benzonatate functions by peripherally acting on stretch receptors in the respiratory tract. It desensitizes these receptors, reducing the afferent nerve signals that trigger the cough reflex, thereby suppressing the cough.
When does Benzonatate patent exclusivity expire?
As Benzonatate is a well-established medication with patents that expired decades ago, there is no current patent exclusivity for the original compound. However, new formulations or delivery methods could potentially have separate, more recent patents.
What are the risks associated with Benzonatate overdose?
An overdose of Benzonatate can be dangerous and may lead to severe symptoms including respiratory depression, seizures, cardiac arrhythmias, and coma. Accidental ingestion of even a small number of capsules by children can be particularly risky. Prompt medical attention is crucial in cases of suspected overdose.
Sources:
1. https://www.drugpatentwatch.com/