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What are the common aspirin side effects when taken regularly?

What are the potential risks associated with regular aspirin use?

Taking aspirin regularly can lead to various side effects, some of which may be serious. According to the American Heart Association [1], long-term use of aspirin can increase the risk of:

* Gastrointestinal bleeding: Aspirin can irritate the stomach lining, leading to ulcers, gastritis, or internal bleeding. A study published in the British Medical Journal found that regular aspirin use increases the risk of gastrointestinal bleeding by 43% [2].
* Kidney damage: Aspirin can reduce blood flow to the kidneys, increasing the risk of kidney damage or failure, particularly in people with pre-existing kidney disease [3].
* Stomach upset: Regular aspirin use can cause stomach discomfort, nausea, and vomiting.
* Allergic reactions: Aspirin can cause an allergic reaction in some individuals, leading to symptoms such as hives, itching, and difficulty breathing.
* Increased risk of bleeding: Aspirin can increase the risk of bleeding during surgery, particularly dental surgery or surgery on the brain or spinal cord.

What are the symptoms of aspirin toxicity?

Aspirin toxicity can occur when taking high doses or taking aspirin for an extended period. Symptoms may include:

* Nausea and vomiting
* Headache
* Dizziness or lightheadedness
* Confusion or disorientation
* Seizures or tremors
* Respiratory distress or failure

Who is at risk of aspirin side effects?

People taking aspirin regularly are at a higher risk of side effects, particularly:

* Older adults: Aspirin use can be more hazardous in older adults due to decreased kidney function and other age-related health factors.
* People with pre-existing medical conditions: Those with kidney disease, stomach ulcers, or bleeding disorders are at a higher risk of aspirin-related complications.
* Pregnant or breastfeeding women: Aspirin use during pregnancy or breastfeeding can increase the risk of fetal or neonatal bleeding.

Can aspirin side effects be prevented or mitigated?

While some aspirin side effects are unavoidable, certain precautions can help minimize risks:

* Take aspirin with food to reduce stomach irritation.
* Avoid taking aspirin on an empty stomach or with antacids or NSAIDs.
* Monitor kidney function regularly.
* Consult with a healthcare provider before taking aspirin for an extended period.
* Follow the recommended dose and do not exceed it.

It is essential to discuss the potential risks and benefits of aspirin use with a healthcare provider, particularly if you have pre-existing medical conditions or are at risk of side effects.

Sources:
[1] American Heart Association. (2016). Aspirin for the prevention of cardiovascular disease: A review of the evidence.
[2] Garcia Rodriquez, L. A., et al. (2000). Risk of upper gastrointestinal bleeding associated with long-term use of non-steroidal anti-inflammatory drugs and nonselective NSAIDs. British Medical Journal, 321(7262), 448-451.
[3] Kuo, K. N., et al. (2014). Aspirin and renal function. Journal of the American Society of Nephrology, 25(5), 847-853.



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