Vyzulta is the brand name for latanoprost bunod ophthalmic solution. It’s a prescription eye drop used to lower intraocular pressure in adults with open-angle glaucoma or ocular hypertension.
Key points
- Mechanism: Combines a prostaglandin analog (latanoprost) with a nitric oxide donor (bunod). This helps increase drainage of aqueous humor through multiple outflow pathways, lowering pressure inside the eye.
- Indications: Open-angle glaucoma or ocular hypertension.
- Common side effects: Redness of the eye (conjunctival hyperemia), eye irritation or itching, tearing, dry eye. May also cause eyelash growth or iris color changes like other prostaglandin analogs.
- Serious but less common: Allergic reaction; eye pain, vision changes, severe swelling; corneal problems. If you have a sudden change in vision or eye pain, seek care promptly.
How to use
- Typical dosing: 1 drop in the affected eye(s) once daily, in the evening. Do not exceed once-daily use.
- Technique (general guidance):
- Wash hands before use.
- Tilt head back, pull down the lower eyelid to create a small pocket.
- Instill 1 drop in the pocket, avoiding the dropper touching the eye or any surface.
- Close the eye for 1–2 minutes. Press gently on the inner corner of the eye (lacrimal duct) for 1 minute to reduce systemic absorption.
- If using more than one eye medicine, wait 5–10 minutes between drops.
- If you wear contact lenses, remove them before using the drop and wait about 15 minutes before reinserting.
- Missed dose: If you miss a dose, use it as soon as you remember. If it’s near the time of your next dose, skip the missed dose—do not double up.
Precautions and who should be careful
- Contraindications: Known hypersensitivity to latanoprost bunod or any ingredient in the product.
- Cautions: Use with caution if you have inflammatory eye conditions, active eye infections, or a history of certain eye conditions. Inform your eye care provider if you have a history of uveitis, glaucoma types other than open-angle, or are pregnant or breastfeeding.
- Effects on eye color and lashes: Prolonged use can cause iris pigmentation changes and eyelash growth. These changes may be permanent.
- Systemic effects: Rare with eye drops but can include headaches or dizziness.
Other considerations
- Interactions: Avoid using other prostaglandin-eye drops at the same time unless advised by your provider; space out drops by several minutes.
- Storage: Keep bottle tightly closed; store at room temperature away from light and heat. Do not use after the labeled expiration date. Discard according to the package insert after opening.
- Pregnancy/breastfeeding: Discuss risks and benefits with your healthcare provider.
If you’d like, tell me your specific question (e.g., how it compares to another glaucoma medication, dosing for a specific situation, or side effects you’re experiencing), and I can tailor the info.