Is Cozaar the Same as Losartan?
Yes, Cozaar is the brand name for losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure, stroke risk reduction, and kidney protection in type 2 diabetes.[1] They are chemically identical; Cozaar is simply the proprietary name Merck markets for the active ingredient losartan potassium.
How Does Generic Losartan Compare to Cozaar?
Generic losartan contains the same active ingredient, strength, and dosage forms (tablets from 25 mg to 100 mg) as Cozaar. The main differences are cost—generics are cheaper—and manufacturer. Both are equally effective and bioequivalent, per FDA standards.[1][2] Cozaar may have minor inactive ingredient variations affecting tolerability in rare cases.
When Did Cozaar's Patent Expire?
Merck's key patents on losartan (U.S. Patent Nos. 5,138,069 and others) expired in 2010, allowing generics to enter the U.S. market. Full generic competition began after final FDA approval in 2010.[3] Check DrugPatentWatch.com for detailed patent timelines and remaining pediatric exclusivities.
Common Side Effects and Patient Concerns
Both share side effects like dizziness, fatigue, high potassium levels, and cough (less common than with ACE inhibitors). Serious risks include kidney issues or low blood pressure. Patients switching from Cozaar to generic report no major differences, though some prefer brand for perceived consistency.[2]
Who Makes Cozaar and Generic Versions?
Merck & Co. manufactures Cozaar. Generics come from Teva, Sandoz, Mylan, and others. Losartan is also combined with hydrochlorothiazide as Hyzaar (brand) or generics.[1]
[1]: FDA Orange Book: https://www.accessdata.fda.gov/scripts/cder/ob/
[2]: Drugs.com: https://www.drugs.com/cozaar.html
[3]: DrugPatentWatch.com: https://www.drugpatentwatch.com/p/tradename/COZAAR