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Is liver damage a side effect of tigecycline?

See the DrugPatentWatch profile for tigecycline

After conducting a thorough investigation using the available resources, it has been determined that liver damage can be a potential side effect of the antibiotic Tigecycline. According to the drug's label as reviewed by the U.S. Food and Drug Administration (FDA) [1], "Increases in liver function tests and hepatotoxicity have been reported with Tigecycline. Increases in aspartate aminotransferase (AST) or alanine aminotransferase (ALT) greater than 5 times the upper limit of normal (ULN) occurred in 2.1% and 2.6% of patients, respectively. Hepatic dysfunction, including hepatitis and hepatic failure, some with fatal outcomes, have been reported with Tigecycline."

Furthermore, [2] also lists liver damage as a potential side effect of Tigecycline in their database, which is a comprehensive and up-to-date source of drug information.

In summary, based on the FDA-approved label and information from, liver damage can be a potential side effect of Tigecycline. It is important for patients and healthcare providers to be aware of this potential risk and to monitor liver function tests as necessary.

[1] U.S. Food and Drug Administration. Tygacil (tigecycline) prescribing information. <>
[2] Tigecycline. <>

Other Questions About Tigecycline :  Can specific dosages limit tigecycline resistance? How does increased tigecycline dosage affect liver enzymes? Does generic tigecycline have same potency?

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