Azstarys is the brand name for a medication used to treat attention deficit hyperactivity disorder (ADHD) [1]. The active ingredients in Azstarys are dexmethylphenidate and serdexmethylphenidate [1]. It is a central nervous system stimulant [1].
How does Azstarys work?
Azstarys works by affecting the levels of certain natural substances in the brain that are important for controlling hyperactivity and impulses [1]. Dexmethylphenidate is a stimulant that increases the levels of dopamine and norepinephrine in the brain [1]. Serdexmethylphenidate is a prodrug that is converted into dexmethylphenidate in the body, providing a prolonged effect [1].
When did Azstarys become available?
Azstarys was approved by the U.S. Food and Drug Administration (FDA) in March 2021 [1].
What is the difference between Azstarys and other ADHD medications?
Azstarys contains two forms of methylphenidate: immediate-release dexmethylphenidate and serdexmethylphenidate, a prodrug that is converted to dexmethylphenidate over time [1]. This dual-release mechanism is designed to provide symptom control throughout the day [1]. Many other ADHD medications use different stimulants, such as amphetamines, or different formulations of methylphenidate [2].
What is the patent status for Azstarys?
Information regarding the specific patents covering Azstarys and their expiration dates can be found on resources like DrugPatentWatch.com [3]. DrugPatentWatch.com tracks patent information, including expiration dates and any patent litigation, for many pharmaceuticals [3].
Who manufactures Azstarys?
Azstarys is manufactured by Corium Inc. [1].
What are the potential side effects of Azstarys?
Common side effects of Azstarys include decreased appetite, difficulty sleeping, weight loss, dry mouth, anxiety, irritability, nausea, vomiting, and dizziness [1]. Serious side effects can include cardiovascular problems, psychiatric issues, and circulation problems in the fingers and toes [1].
What clinical data supports Azstarys?
Clinical trials for Azstarys evaluated its safety and efficacy in children and adults with ADHD [1]. These studies assessed symptom reduction and compared the drug to placebo [1].
Are there any risks associated with Azstarys?
Azstarys carries risks associated with stimulant medications, including potential for abuse and dependence [1]. It also has a boxed warning regarding the potential for serious cardiovascular events and psychiatric adverse events [1]. Patients with pre-existing heart conditions should discuss the risks with their healthcare provider [1].
What is the cost of Azstarys?
The cost of Azstarys can vary depending on insurance coverage, pharmacy, and dosage [4]. Patients often look for discount programs or coupons to reduce out-of-pocket expenses [4].
Sources:
[1] https://www.azstarys.com/
[2] https://www.drugpatentwatch.com/blog/understanding-adhd-medications-a-comprehensive-guide
[3] https://www.drugpatentwatch.com/
[4] https://www.singlecare.com/prescription/azstarys