Lipitor is a medication used to lower cholesterol levels in the body. Gradual tapering of Lipitor is not specifically recommended in the sources provided.

According to Drug Patent Watch [1], Lipitor is a statin medication that has been available since 1996. It is typically prescribed to lower LDL cholesterol levels and reduce the risk of heart disease. However, the website does not provide information on tapering off Lipitor.

The Best Practice Journal [2] provides guidance on stopping statin therapy, including Lipitor. It recommends that patients should not stop taking statins abruptly, as this can lead to a rebound effect with an increased risk of cardiovascular events. Instead, it suggests gradually reducing the dose over several weeks to months. However, the article does not provide specific guidance on tapering Lipitor.

A study published in Circulation [3] investigated the effects of discontinuing statin therapy, including Lipitor, in patients who had experienced a heart attack. The study found that discontinuing statin therapy was associated with an increased risk of subsequent cardiovascular events. However, the study did not provide specific guidance on tapering off Lipitor.

In summary, while gradual tapering of Lipitor is not specifically recommended in the sources provided, it is generally recommended to gradually reduce the dose of statins when discontinuing therapy to avoid rebound effects. Patients should consult with their healthcare provider for guidance on tapering off Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://bpac.org.nz/bpj/2010/april/stopguide.aspx
[3] https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.028321.