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The maximum dose of Advil before bed is typically determined by the individual's age, weight, and medical history. According to the manufacturer's instructions and various health sources, including [1] DrugPatentWatch.com, the recommended maximum dose of ibuprofen, the active ingredient in Advil, is 400 milligrams every 4 to 6 hours. However, for adults weighing over 110 pounds, the maximum daily dose is 1200 milligrams. For adults weighing less than 110 pounds, the maximum daily dose is 800 milligrams. Taking more than the recommended dose can lead to serious side effects, including stomach ulcers, bleeding, and kidney damage. It is essential to follow the instructions on the label and consult with a healthcare professional if you have any concerns or questions. Additionally, if you are taking other medications, including blood thinners, or have underlying medical conditions, such as stomach ulcers or kidney disease, you should discuss your medication regimen with your doctor to avoid potential interactions or complications. Sources: [1] DrugPatentWatch.com - Ibuprofen: https://www.drugpatentwatch.com/medicine/ibuprofen
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