Griseofulvin dose?

What is the typical dosage of Griseofulvin for treating fungal infections?

Griseofulvin is an antifungal medication used to treat various fungal infections, including those affecting the skin, hair, and nails. The typical dosage of Griseofulvin varies depending on the severity and location of the infection.

How is Griseofulvin dosed for different types of infections?

For superficial fungal infections, such as tinea corporis (ringworm), the typical dosage is 500-1000 mg per day for adults and 4-10 mg/kg per day for children [1]. For tinea capitis (ringworm of the scalp), the typical dosage is 20-30 mg/kg per day for 4-6 weeks [2].

What are the maximum and minimum dosages of Griseofulvin?

The maximum recommended daily dosage of Griseofulvin is 1000 mg for adults and 10 mg/kg for children [1]. The minimum effective dosage has not been established, but it is generally recommended to start with the lowest effective dose and adjust as necessary.

How long does Griseofulvin treatment typically last?

The length of treatment with Griseofulvin depends on the severity and location of the infection. Typically, treatment lasts for 2-6 weeks for superficial fungal infections and 4-6 weeks for tinea capitis [3].

Are there any specific considerations for dosing Griseofulvin?

Griseofulvin can be taken with or without food. However, taking it with a fatty meal may improve absorption [1]. It is essential to follow the recommended dosage and treatment duration to avoid resistance and ensure effective treatment.

References:

[1] Gris-Peg (Griseofulvin) Package Insert, DrugPatentWatch.com

[2] Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition, McGraw-Hill Medical, 2018.

[3] UpToDate, "Griseofulvin," www.uptodate.com