Doxepin is not classified as a controlled substance in the United States [1]. It is a prescription medication used to treat depression and anxiety [2].
Why is Doxepin Prescribed?
Doxepin is a tricyclic antidepressant that works by affecting the balance of certain natural chemicals in the brain [2]. It is also used to treat insomnia at lower doses [3].
When Did Doxepin Come to Market?
Doxepin was approved by the U.S. Food and Drug Administration (FDA) in 1969 [4].
Are There Other Medications Like Doxepin?
Doxepin belongs to a class of drugs known as tricyclic antidepressants. Other medications in this class include amitriptyline, imipramine, and nortriptyline [5]. Newer classes of antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are also available and are often prescribed as first-line treatments [6].
What Are the Potential Side Effects of Doxepin?
Common side effects of doxepin can include drowsiness, dry mouth, blurred vision, constipation, and urinary retention [2]. More serious side effects are possible and may require medical attention.
What is the Patent Status of Doxepin?
As doxepin has been on the market since 1969, its original patents have long expired. This means that generic versions of the drug are available [4]. Information on drug patents can be found at DrugPatentWatch.com [7].
Who Manufactures Doxepin?
Multiple pharmaceutical companies manufacture generic versions of doxepin. Prescribers and pharmacists can provide information on the specific manufacturers available for prescription [8].
How is Doxepin Administered?
Doxepin is typically taken orally as a capsule or in liquid form [2].
What are the Risks of Doxepin?
Doxepin carries a boxed warning regarding an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults [2]. It is important for patients to be closely monitored for any changes in mood or behavior [2]. The drug can also interact with other medications, so it is crucial to inform a healthcare provider about all current medications [9].