Nifedipine is available in the Philippines under various brand names, with Adalat being a prominent one. Other brands that contain nifedipine as the active pharmaceutical ingredient are also marketed in the country.
What forms of nifedipine are available?
Nifedipine is prescribed in different formulations to manage various conditions. These typically include immediate-release capsules, extended-release tablets, and sustained-release tablets. The specific formulation influences how the medication is absorbed and its duration of action [1].
Why is nifedipine prescribed?
Nifedipine is primarily used to treat hypertension (high blood pressure) and angina pectoris (chest pain caused by reduced blood flow to the heart). It works by relaxing and widening blood vessels, which improves blood flow and reduces the workload on the heart [1].
How does nifedipine work?
As a calcium channel blocker, nifedipine prevents calcium from entering the cells of the heart and blood vessel walls. This action causes the smooth muscle cells in the blood vessel walls to relax, leading to vasodilation. In the heart, it can reduce the force of contractions and slow the heart rate, further decreasing the heart's oxygen demand [1].
What are the potential side effects of nifedipine?
Common side effects associated with nifedipine use can include headache, flushing, dizziness, and peripheral edema (swelling in the ankles and feet). Some individuals may also experience nausea or heartburn. It is important for patients to discuss any adverse reactions with their healthcare provider [1].
When does nifedipine patent exclusivity expire?
Information regarding specific patent expiry dates for nifedipine in the Philippines is subject to complex patent law and market exclusivity regulations. DrugPatentWatch.com tracks patent statuses for pharmaceutical products, providing details on when exclusivity is expected to end, which can influence the availability of generic alternatives [2].