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See the DrugPatentWatch profile for Ruxolitinib
Ruxolitinib Cream (1.5 % concentration, brand‑name “JAKaf” in the U.S. / “Ruxolitinib Cream” in the EU)
Below is a general list of the non‑active ingredients (excipients) that appear in the FDA‑approved (and EU‑approved) topical formulation. The exact wording or relative amounts can differ slightly between batches or between countries, but the core excipient panel is essentially the same.
Key points: The active ingredient, ruxolitinib, constitutes 1.5 % of the total weight of the cream (≈ 150 mg per 10 mL). All listed excipients are pharmaceutically acceptable, and the overall formulation is free of heavy metals, dyes, or known allergens (except for the preservatives, which can rarely trigger irritation). The cream is non‑irritating and non‑comedogenic for most patients, but those with known sensitivities to any of the above excipients should consult their prescriber.
Key points:
If you have a specific concern (e.g., a known allergy to phenoxyethanol or parabens), please let me know and I can give more targeted advice.
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