Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body. Painkillers, on the other hand, are medications used to relieve pain. While both medications are effective in their respective uses, there are potential risks associated with combining them.

According to DrugPatentWatch [1], there are no known drug interactions between Lipitor and painkillers. However, it is important to note that this does not mean that there are no risks associated with taking these medications together.

A study published in the US National Library of Medicine [2] found that combining Lipitor with certain painkillers, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen, can increase the risk of muscle damage and kidney problems. This is because both Lipitor and NSAIDs are metabolized by the liver, and taking them together can lead to an overload of the liver, potentially causing liver damage.

Additionally, the Geneseo Student Health and Counseling Services [3] warns that combining Lipitor with certain painkillers, such as acetaminophen, can increase the risk of liver damage. This is because both Lipitor and acetaminophen are metabolized by the liver, and taking them together can lead to an overload of the liver, potentially causing liver damage.

In conclusion, while there are no known drug interactions between Lipitor and painkillers, there are potential risks associated with combining them. It is important to consult with a healthcare provider before taking any new medications, and to inform them of all medications currently being taken in order to avoid potential complications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/
[3] https://www.geneseo.edu/sites/default/files/sites/health/Drug%20Interactions.pdf