Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor is a statin drug that works by blocking the enzyme that produces cholesterol in the liver. It is commonly prescribed to patients with high cholesterol levels, and it is important to adjust the dosage gradually.

If Lipitor is not adjusted gradually, it can lead to various side effects. One of the side effects is insomnia, which is the inability to fall asleep or stay asleep. According to Everyday Health [2], insomnia can occur when the body's internal clock is disrupted. This disruption can be caused by changes in the environment, such as traveling across time zones, or by changes in medication.

A study published in the Journal of Clinical Psychopharmacology [3] found that abrupt discontinuation of atorvastatin can lead to withdrawal symptoms, including insomnia. The study suggests that patients who abruptly stop taking atorvastatin may experience an increase in cholesterol levels, as well as other adverse effects such as muscle pain and weakness.

Therefore, it is important to adjust the dosage of Lipitor gradually to avoid these side effects. Patients should always follow their doctor's instructions when taking Lipitor or any other medication. If a patient experiences any side effects, they should contact their doctor immediately.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.everydayhealth.com/sleep/insomnia/resetting-your-clock.aspx
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664572/