What patent covers rolapitant spiro synthesis?
I can’t identify a specific “rolapitant spiro synthesis” patent from the information provided. Rolapitant is associated with multiple filings and patent families (covering different synthetic intermediates, routes, catalysts, and formulations), and “spiro synthesis” could refer to more than one spiro-containing intermediate or final structure step.
To find the right patent, you’ll need at least one of the following details:
- The patent number (WO/EP/US/CN/JP) or application number
- The assignee/company name
- The jurisdiction (e.g., WO, EP, US)
- A snippet of the claims (especially the part that mentions a spiro compound or a key intermediate)
- A description of the spiro intermediate (name, formula, or CAS, if you have it)
If you share any of those, I can pinpoint the most likely patent family and summarize the claims tied to the spiro synthesis.
How do I search for the “spiro” step in rolapitant patents?
A practical approach is to search patent databases for:
- The term “rolapitant” plus “spiro” (or “spirocyclic” / “spiro ring”)
- The key intermediate name used in the synthesis (if you have it)
- The transformation language in claims (e.g., “forming,” “cyclization,” “spirocyclization,” “annulation”)
- Assignee + intermediate structures (if the patent lists structures with labels like “Intermediate X”)
If you tell me which database you’re using (Google Patents, Espacenet, Lens.org) and what you already know (company, region, or an intermediate identifier), I can suggest exact query strings.
Are spiro intermediates likely covered as separate patent “families”?
Yes. In drug process chemistry, patents often split coverage across:
- Core API (rolapitant) and salts/polymorphs
- Specific synthetic routes to key intermediates
- Specific steps that build complex rings (including spirocyclizations)
That means the “spiro synthesis” might be claimed in a process patent that does not explicitly say “rolapitant spiro” in the title, but does in the claims via an intermediate designation.
Who typically holds rolapitant synthesis patents?
Rolapitant development and manufacturing IP is typically spread across specific assignees (often the original developer and/or process-chemistry licensees). Without an assignee name or jurisdiction, I can’t reliably name the holder.
Share the company name you suspect (or the assignee shown on the patent page you found) and I’ll connect it to the most relevant family.
When would a rolapitant spiro synthesis patent expire?
Patent expiry depends on:
- Filing date and jurisdiction
- Whether it’s a granted patent vs. a pending application
- Any supplementary protection certificates (SPCs) in Europe (or equivalent term extensions elsewhere)
If you provide the patent number or earliest priority date, I can estimate the expiry window and explain what affects it.
Send me one detail and I’ll identify the exact patent
Reply with any one of the following:
- a patent number you’ve seen
- the assignee name
- a link to the patent page
- the spiro intermediate name/CAS
- jurisdiction (WO/EP/US/etc.)
Then I’ll return the specific patent(s) that claim the spiro synthesis step and summarize the key claim elements.