Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. Monoamine oxidase inhibitors (MAOIs) are a class of medications used to treat depression and anxiety.

There is limited information available on the interaction between Lipitor and MAOIs. However, it is generally not recommended to take Lipitor with MAOIs due to the potential for serious drug interactions.

MAOIs can increase the levels of certain neurotransmitters in the brain, such as serotonin, norepinephrine, and dopamine. Lipitor can also affect the levels of these neurotransmitters. When taken together, the combination can lead to a potentially life-threatening condition called serotonin syndrome [1]. Symptoms of serotonin syndrome can include agitation, confusion, rapid heart rate, high blood pressure, muscle rigidity, and fever.

It is important to inform your healthcare provider if you are taking MAOIs or have taken them within the past two weeks before starting Lipitor. Your healthcare provider may recommend alternative medications to Lipitor that do not interact with MAOIs [2][3].

Sources:
[1] https://www.everydayhealth.com/drugs/lipitor
[2] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[3] https://www.drugs.com/drug-class/monoamine-oxidase-inhibitors.html