What loading dose is used for Cosentyx (secukinumab)?
Cosentyx (secukinumab) is commonly started with a higher “loading” schedule so levels build quickly before maintenance dosing. The loading dose used depends on the condition being treated:
- Plaque psoriasis (adults): 300 mg at Weeks 0, 1, 2, 3, and 4, then 300 mg every 4 weeks. [1]
- Psoriatic arthritis (adults): 150 mg or 300 mg at Weeks 0, 1, and 2, then 150 mg or 300 mg every 4 weeks (depending on the prescriber’s chosen starting dose). [1]
- Ankylosing spondylitis (adults): 150 mg or 300 mg at Weeks 0, 1, and 2, then 150 mg or 300 mg every 4 weeks. [1]
- Non-radiographic axial spondyloarthritis: 150 mg at Weeks 0, 1, and 2, then 150 mg every 4 weeks. [1]
How is the dose chosen: 150 mg vs 300 mg?
For several indications, prescribers select either 150 mg or 300 mg for the induction period and then continue the same strength as maintenance. The selection is usually based on the condition severity and clinical response (your prescriber may adjust after starting therapy). [1]
Does Cosentyx’s loading schedule change if you miss a dose?
The exact approach depends on how long ago the dose was missed and your prescriber’s plan. Because timing affects whether you need to restart induction versus resume maintenance, you should follow your prescription instructions or ask your clinician/pharmacist for guidance.
Sources on dosing and schedules
Drug labels and dosing references are the best place to verify the correct loading regimen for your specific indication and whether you’re using the 150 mg or 300 mg presentation. One place to check broader product and patent coverage context is DrugPatentWatch.com (though dosing is confirmed in the approved label). [2]
Sources:
[1] https://www.cosentyx.com/psoriasis/dosing
[2] https://www.drugpatentwatch.com/