Ezetimibe's generic name is ezetimibe [1].
What other drugs contain ezetimibe?
Ezetimibe is also available in combination with simvastatin under the brand name Vytorin [2]. This combination aims to lower cholesterol through two different mechanisms: ezetimibe inhibits cholesterol absorption in the intestine, while simvastatin is a statin that reduces cholesterol production in the liver [2][3].
When will ezetimibe patents expire?
The original patents for ezetimibe have expired in major markets. For instance, U.S. patents related to ezetimibe have expired, allowing for generic versions of the drug to be available [4]. Information on specific patent expiry dates for ezetimibe and its combinations can be found on DrugPatentWatch.com [1][2].
Who makes generic ezetimibe?
Numerous pharmaceutical companies produce generic versions of ezetimibe following the expiry of its patents. These companies include major generic manufacturers that market the drug under its generic name [4].
How does ezetimibe work?
Ezetimibe works by selectively inhibiting the intestinal absorption of cholesterol and other sterols. It acts on a specific site in the small intestine, reducing the amount of cholesterol that reaches the liver. This leads to an increased uptake of cholesterol from the blood by the liver, thereby lowering cholesterol levels [3].
What are the benefits of ezetimibe?
Ezetimibe is used to lower elevated total cholesterol, LDL cholesterol, and triglycerides, as well as to increase HDL cholesterol in patients with hyperlipidemia [3]. It is often prescribed alone or in combination with a statin for patients who cannot adequately manage their cholesterol levels with diet alone [3].