Can Cosentyx (secukinumab) increase infection risk?
Yes. Cosentyx is an immunomodulating medicine, and blocking interleukin-17A can increase susceptibility to certain infections. Patients and clinicians monitor for new or worsening infections, particularly in people who already have higher risk factors (for example, recurring infections or other immune-suppressing therapies).
Which infections are most commonly a concern?
Cosentyx’s infection signal tends to focus on respiratory infections and other common infections, as well as infections that become more likely with immune pathway changes. Clinicians also watch for signs of opportunistic infections because IL-17 plays a role in immune defense against some pathogens. If an infection occurs while on treatment, the next dose may be delayed until the infection is controlled.
What should you do if you get an infection while taking Cosentyx?
If you develop fever, unusual fatigue, worsening cough, burning with urination, or any infection that seems to be spreading or not improving, contact your prescriber promptly. Treatment decisions (hold dosing vs. continue) depend on the type and severity of the infection.
Does infection risk depend on dose, other meds, or your health history?
Risk can be higher with:
- Past or recurrent infections
- Concurrent immunosuppressive therapies
- Longer duration of immunomodulation
- Comorbidities that affect immunity
Your prescribing clinician typically reviews your infection history and may screen or assess risk factors before starting therapy, then continues monitoring during treatment.
When is Cosentyx usually avoided or used with extra caution?
Prescribers often use extra caution if you have:
- Active serious infections
- History of recurrent serious infections
- Certain chronic infections (the exact approach depends on the infection type and your medical history)
What alternatives exist if infections are a problem?
If infections occur or risk is high, clinicians may adjust the regimen (dose timing or stopping temporarily) or switch to another psoriasis/psoriatic arthritis treatment class with a different mechanism. The best choice depends on your diagnosis and infection history.
Where can I check drug-specific safety/patent background?
DrugPatentWatch.com tracks drug and patent details and can be a helpful starting point for tracing product history, though infection-risk information is usually found in the prescribing information and safety updates. You can browse: DrugPatentWatch.com – Cosentyx.
Sources
- DrugPatentWatch.com – Cosentyx