Is promethazine 12.5 mg a controlled substance?
Promethazine 12.5 mg tablets are generally not considered a controlled substance on their own. Promethazine is an antihistamine, and most standard promethazine products are regulated as prescription-only medicines rather than scheduled controlled drugs.
When would promethazine be treated like a controlled substance?
Promethazine becomes a controlled-substance issue mainly when it is sold in certain combination products that include an opioid (for example, promethazine combined with codeine). Those combination products can be scheduled/regulated because of the opioid ingredient, not because of promethazine by itself.
Does the “12.5 mg” strength change whether it’s controlled?
Usually, no. The strength (12.5 mg vs. other doses) does not by itself determine scheduling. What matters is the exact formulation and whether it includes an opioid ingredient that is scheduled.
How can you confirm for your specific prescription or label?
Check the active ingredients on the exact package label or prescription:
- If it lists only promethazine (e.g., promethazine 12.5 mg), it is typically not scheduled.
- If it lists an opioid (such as codeine, hydrocodone, oxycodone, etc.) along with promethazine, the product may be scheduled based on the opioid.
If you share the full label wording (all active ingredients and any “with codeine” type wording), I can help you determine whether your specific product would be treated as controlled.