What is the difference between norditropin flexpro and norditlet?

Main Differences Between Norditropin FlexPro and Norditropin NordiLet

Norditropin FlexPro and Norditropin NordiLet are both pre-filled, multi-dose injection pens delivering somatropin (human growth hormone) from Novo Nordisk for growth hormone deficiency and related conditions. FlexPro uses a pen-injector with a built-in needle cover, while NordiLet has a simpler design without it.[1]

FlexPro holds larger volumes (5 mg/1.5 mL, 10 mg/1.5 mL, 15 mg/1.5 mL) for fewer dose changes in long-term use. NordiLet comes in smaller sizes (5 mg/1.5 mL, 10 mg/1.5 mL).[1]

How Dosing and Priming Work

Both pens dose in 0.05 mg increments via a dial. FlexPro requires 2 priming clicks before each injection; NordiLet needs 5 clicks. FlexPro shows remaining doses numerically on the label; NordiLet uses a window with color-changing dots.[1][2]

Ease of Use for Patients

FlexPro is needle-free until injection (needle emerges on press), preferred by needle-averse users or kids. NordiLet exposes the needle earlier during setup. Both are disposable, stored at room temperature up to 3 weeks after first use.[1]

Users report FlexPro as more discreet and less intimidating, especially for children, while NordiLet feels more basic and familiar to long-time patients.[2]

Availability and Which to Choose

NordiLet has been phased out in many markets (discontinued in the US around 2018), with FlexPro as the primary option now. Check with pharmacies or prescribers for regional stock. Switch between them requires no dose adjustment since concentration matches.[1][3]

| Feature | Norditropin FlexPro | Norditropin NordiLet |
|---------|---------------------|----------------------|
| Needle handling | Hidden until injection | Exposed during prep |
| Volume options | Up to 15 mg/1.5 mL | Up to 10 mg/1.5 mL |
| Priming clicks | 2 | 5 |
| Dose display | Numeric label | Color dots in window |
| Status | Current standard | Mostly discontinued |

[1]: Novo Nordisk Norditropin Prescribing Information
[2]: Patient forums and reviews on Drugs.com
[3]: FDA drug database on Norditropin formulations