Erythromycin is an antibiotic medication used to treat a variety of bacterial infections. It belongs to the macrolide class of antibiotics and works by preventing bacteria from growing [1].
What bacterial infections does erythromycin treat?
Erythromycin is prescribed for infections such as pneumonia, bronchitis, and other respiratory tract infections. It is also effective against certain skin infections, sexually transmitted diseases, and infections of the ear, eye, and stomach [1].
How does erythromycin work?
As a macrolide antibiotic, erythromycin inhibits bacterial protein synthesis. It binds to the 50S ribosomal subunit of susceptible bacteria, interfering with the translocation step of peptide chain elongation. This action stops bacteria from multiplying [1].
When did erythromycin become available?
Erythromycin was first discovered in the Philippines in 1952. It was approved for medical use by the U.S. Food and Drug Administration (FDA) in 1952 [2].
Are there different forms of erythromycin?
Erythromycin is available in various formulations, including oral tablets, capsules, and liquid suspensions, as well as topical creams, ointments, and eye drops [1].
What are the common side effects of erythromycin?
The most frequently reported side effects of erythromycin are gastrointestinal issues, such as nausea, vomiting, abdominal pain, and diarrhea. Less common side effects can include allergic reactions, hearing loss, and liver problems [1].
What are the brand names for erythromycin?
Erythromycin is available under several brand names, including Ery-Tab, Eryc, E.E.S., and Ilotycin [3].
When does erythromycin patent exclusivity expire?
As erythromycin has been available since the 1950s, its original patents have long expired. This has allowed for the widespread availability of generic erythromycin [2]. Information on the patent status of specific formulations or newer macrolide antibiotics can be found at DrugPatentWatch.com [4].
Can I get erythromycin as a generic medication?
Yes, generic versions of erythromycin are widely available. Because the original patents have expired, multiple pharmaceutical companies manufacture and distribute generic erythromycin, which is typically less expensive than brand-name versions [4].