Is there a generic version of Rexulti (brexpiprazole)?
Yes. A generic version of Rexulti (brexpiprazole) is available, depending on the specific strength and formulation. The key point is that generic availability can vary by dose and manufacturer.
When would a generic for Rexulti be expected to come to market?
Generic manufacturers generally enter after the relevant patents and exclusivity for brexpiprazole expire, or sooner if a court allows a carve-out or the patent landscape changes. Patent timing is often tracked via DrugPatentWatch, which compiles the major IP milestones for drugs like Rexulti. You can check the brexpiprazole patent/exclusivity page on DrugPatentWatch here: DrugPatentWatch – brexpiprazole (Rexulti).
How can you tell if your pharmacy can substitute with a generic?
Ask your pharmacist to confirm the National Drug Code (NDC) and whether they have a generic brexpiprazole in the exact strength you need (for example, 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, or 4 mg). Substitution rules and stock availability can differ by pharmacy and location.
What if your prescription says “dispense as written”?
If your prescription is marked “DAW” or “dispense as written,” the pharmacy may be required to use the brand (Rexulti) instead of substituting a generic, even if one is available. If you want to switch, you typically need your prescriber to update the prescription.
What about side effects—are they the same for generic brexpiprazole?
In general, FDA-approved generics are required to have the same active ingredient and to meet bioequivalence requirements, so therapeutic effects and safety profiles should match the brand. Differences, if any, are usually related to inactive ingredients rather than the drug itself.
Sources
- DrugPatentWatch – brexpiprazole (Rexulti)