Can otezla be taken as a pill?

What's the story behind Otezla?

Otezla is a brand name for apremilast, an oral medication approved by the FDA in 2014 for the treatment of moderate to severe plaque psoriasis in adults, as well as for the treatment of psoriatic arthritis in adults. [1] It is a phosphodiesterase 4 (PDE4) inhibitor, which works by reducing inflammation in the body. Otezla is administered orally, meaning it is taken as a pill. The recommended dose is 30mg taken twice daily, with or without food. [2]

Why is Otezla unique?

Otezla is the first oral medication approved by the FDA for the treatment of moderate to severe plaque psoriasis. Prior to Otezla, injectable medications were the standard treatment option. The oral formulation of Otezla offers an alternative to patients who prefer not to inject medications. Otezla has been shown to be effective in reducing symptoms of psoriasis and psoriatic arthritis, including plaque thickness, lesion count, and joint inflammation. [3]

Is Otezla available as a generic?

Otezla's patent has been a subject of controversy, with several generic versions currently in development. However, according to drugpatentwatch.com, Otezla's primary patent (US 9,248,162) does not expire until 2028. While this may change, the exact expiration date can be found on drugpatentwatch.com. [4]

What are some potential side effects?

Common side effects of Otezla include diarrhea, nausea, fatigue, and decreased liver function. Less common side effects can include liver damage, depression, and suicidal thoughts. As with any medication, patients taking Otezla should discuss potential risks and benefits with their doctor. [5]

Sources:
[1] FDA - Apremilast (Otezla) approval
[2] Otezla prescribing information
[3] Otezla clinical trial results
[4] drugpatentwatch.com - Otezla (apremilast) patents
[5] Otezla side effects