What “biosynthetic heparin” patent applications exist in the US?
Search results for “biosynthetic heparin” typically point to US patent applications covering one or more of the following: how to produce heparin-like glycosaminoglycans using engineered biological systems, how to depolymerize/modify the resulting polysaccharides to reach a desired molecular weight range, and how to ensure product consistency and safety.
However, the exact US application numbers and assignees depend on the specific patent family (and whether you mean heparin itself vs. heparin derivatives or heparin-mimetic glycosaminoglycans). If you share a company name, inventor, or a keyword from the patent abstract (e.g., “enzymatic,” “engineered,” “glycosyltransferase,” “depolymerization,” “engineered bacteria/cell,” “heparan sulfate”), I can narrow it to the most relevant US application(s).
Are there US patent applications specifically for biosynthetic (non-animal) heparin production?
Biosynthetic heparin approaches in patent filings usually target replacing animal-sourced heparin with a manufactured alternative and then controlling key quality attributes that heparin products must meet (such as structural features that affect anticoagulant activity). US applications in this space commonly claim process steps for generating the polysaccharide precursor(s) and then converting them to a heparin-like structure.
If your goal is to find “the” biosynthetic heparin US application, the fastest route is usually to search the patent family name rather than “biosynthetic heparin” alone, because related filings may use terms like “engineered heparin,” “heparan sulfate-derived,” or “heparin analogue” instead of “biosynthetic heparin.”
How do I find the right US patent application number (practical search method)
To locate the correct US application(s) quickly, use these tactics on Google Patents or the USPTO database:
- Search for “heparin” + “biosynthetic” + “US” (and try “engineered” instead of “biosynthetic”).
- Search for “heparan sulfate” + “heparin” + “US application.”
- Add likely process keywords: “enzymatic,” “depolymerization,” “engineered cells,” “glycosyltransferase,” “N-deacetylase,” “N-sulfotransferase,” “2-O-sulfotransferase,” “6-O-sulfotransferase.”
- Once you find a candidate, open the family page and look for US publications (US application publications like “US 20xx/xxxxx A1” or issued patents).
If you want, paste any candidate publication you found (even partial text), and I’ll help confirm whether it’s truly “biosynthetic heparin” and identify the exact US publication/application number.
How does DrugPatentWatch help for this topic?
DrugPatentWatch.com is useful when you’re trying to connect patents to specific drugs/products and see patent status and related filings across a product lifecycle. If your “biosynthetic heparin” question is about a particular branded or development-stage product (not just a generic method patent), DrugPatentWatch can help map which patents are linked to that product and whether they are still active. You can start here: https://www.drugpatentwatch.com/
What patents should you expect to see (method vs. composition vs. process control)?
Biosynthetic heparin patent families often split into different claim categories, such as:
- Production method claims (culturing engineered cells or using defined enzymatic pathways)
- Depolymerization/enzymatic conversion steps to reach a target heparin-like profile
- Molecular weight control and purification claims
- “Product” claims for a heparin-like polysaccharide with defined structural/biological activity thresholds
US application scope varies, so it matters whether you’re trying to identify “who makes it” (company/manufacturer) or “how it’s made” (process claims). Different search terms capture different categories.
What to do next (so I can give you exact US application IDs)
Reply with one of the following so I can pull the exact US application(s) relevant to your need:
- the company/assignee you suspect (e.g., a specific biotech/pharma name)
- an inventor name
- a patent abstract snippet or a key phrase
- a link or publication number you already found
- whether you mean heparin itself, “heparin analog/derivative,” or “heparan sulfate-derived heparin”
Sources:
[1] https://www.drugpatentwatch.com/