Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation [1]. According to Insider, it is generally safe to take Advil after drinking alcohol, but it is recommended to wait at least six hours after drinking before taking ibuprofen [2]. The reason for this is that both alcohol and ibuprofen can irritate the stomach lining and increase the risk of gastrointestinal bleeding. Taking them together can further increase this risk, especially if taken on an empty stomach [2, 3].

Additionally, mixing alcohol and ibuprofen can also increase the risk of liver damage, especially in heavy drinkers [3]. It is important to note that excessive alcohol consumption can impair the liver's ability to metabolize drugs, including ibuprofen, which can lead to an increased risk of adverse effects [3].

In summary, it is generally safe to take Advil after drinking alcohol, but it is recommended to wait at least six hours after drinking and to take it with food to reduce the risk of gastrointestinal bleeding. However, it is important to limit alcohol consumption and to talk to a healthcare provider if you have any concerns about taking ibuprofen or other medications with alcohol [2, 3].

Sources:
[1] DrugPatentWatch. (n.d.). Advil. Retrieved from https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] Insider. (2021, March 15). Is it safe to take ibuprofen after drinking? Retrieved from https://www.insider.com/guides/health/ibuprofen-and-alcohol
[3] Rehab 4 Addiction. (2021, March 1). The risks of mixing ibuprofen and alcohol. Retrieved from https://www.rehab4addiction.co.uk/guides/risks-mixing-ibuprofen-alcohol