What side effects can Advil (ibuprofen) cause?
Advil (ibuprofen) can cause side effects that range from mild stomach upset to serious complications, especially at higher doses or with long-term use. Common side effects include gastrointestinal (GI) effects such as indigestion, heartburn, nausea, vomiting, and stomach pain. Some people also get dizziness or headaches.
What are the more serious side effects to watch for?
Serious side effects are less common but important. Seek urgent medical care if Advil causes signs of GI bleeding or ulcers, such as:
- black or tarry stools
- vomiting blood or material that looks like coffee grounds
- severe or persistent stomach pain
Advil can also raise the risk of cardiovascular events (like heart attack or stroke), particularly with higher doses or prolonged use. Get emergency help for symptoms such as chest pain, trouble breathing, weakness on one side of the body, or sudden trouble speaking.
Allergic reactions can occur as well, including rash, swelling of the face or throat, and difficulty breathing.
Who is at higher risk for bad side effects?
Risk is higher for people who:
- take higher doses or use it for longer than directed
- have a history of stomach ulcers or GI bleeding
- take blood thinners or other drugs that increase bleeding risk
- have certain heart conditions or risk factors for heart disease
- take other NSAIDs at the same time
- have kidney disease or dehydration
Can Advil cause kidney problems?
Yes. NSAIDs like ibuprofen can reduce blood flow to the kidneys, which may worsen kidney function—especially in people who are already at risk (for example, older adults, those with kidney disease, or people who are dehydrated).
Does Advil affect blood pressure or swelling?
It can. Ibuprofen and other NSAIDs may cause fluid retention, swelling (edema), and can raise blood pressure in some people.
What should you do if you miss a dose or take too much?
If you take more than the label recommends, side effects can become more severe, including stomach bleeding and kidney injury. For overdose symptoms (such as severe nausea/vomiting, confusion, extreme drowsiness, fainting, or trouble breathing), get emergency help.
If you’re unsure about how your dose fits your situation (age, other medicines, underlying conditions), check with a pharmacist or clinician before continuing.
Alternatives if NSAID side effects are a concern
Some people who cannot tolerate ibuprofen choose acetaminophen (Tylenol) instead, since it does not work as a NSAID for inflammation and has different risks (not the same stomach/bleeding risk, but it can be harmful to the liver at high doses). A clinician or pharmacist can help match the safest option to your medical history.
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