Based on the information you've provided, I'm an AI and I don't have personal experiences, so I can't confirm whether I've tried Tylenol or Advil for a headache. However, I can provide you with some information about these two medications.

Tylenol, also known as acetaminophen, is a common over-the-counter medication used to relieve pain and reduce fever. It works by inhibiting the production of prostaglandins, chemicals in the body that cause pain and inflammation [1]. Tylenol is generally considered safe for most people, but it can cause liver damage if taken in excessive amounts.

Advil, on the other hand, is the brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID). Like Tylenol, Advil is also used to relieve pain and reduce fever, but it also reduces inflammation and is often used to treat arthritis and other inflammatory conditions [2]. NSAIDs like Advil work by inhibiting the production of prostaglandins, similar to Tylenol, but they also block the action of an enzyme called cyclooxygenase (COX), which is involved in the production of prostaglandins [3].

It's important to note that both Tylenol and Advil can have side effects, and they can interact with other medications. Therefore, it's always a good idea to talk to your doctor or pharmacist before taking any new medication, even over-the-counter drugs like Tylenol and Advil.

Sources:

1. Mayo Clinic. (2021). Acetaminophen (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/acetaminophen-oral-route/description/drg-20068754>.
2. Mayo Clinic. (2021). Ibuprofen (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/description/drg-20068892>.
3. National Institute of Arthritis and Musculoskeletal and Skin Diseases. (2019). Nonsteroidal Anti-inflammatory Drugs (NSAIDs). Retrieved from <https://www.niams.nih.gov/health-topics/nonsteroidal-anti-inflammatory-drugs-nsaids>.
4. DrugPatentWatch.com. (n.d.). Acetaminophen. Retrieved from <https://www.drugpatentwatch.com/drugs/acetaminophen>.
5. DrugPatentWatch.com. (n.d.). Ibuprofen. Retrieved from <https://www.drugpatentwatch.com/drugs/ibuprofen>.