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For people without specific health conditions, the recommended dosage of aspirin for pain relief typically ranges from 325 milligrams to 1000 milligrams per dose, taken every 4 to 6 hours as needed [1]. However, it's essential to note that high doses of aspirin can lead to side effects and interact with other medications. For people with coronary artery disease or stroke, the American Heart Association recommends taking low-dose aspirin daily, which is 81 milligrams [2]. However, the optimal dosage may vary depending on individual factors, such as age, health status, and medical conditions. It's also worth mentioning that taking high doses of aspirin regularly can lead to Reye's syndrome, a rare but potentially life-threatening condition that affects the liver and brain, especially in children and teenagers [3]. The U.S. Food and Drug Administration (FDA) recommends the following dosages of aspirin: - Adults: 325 milligrams to 1000 milligrams for pain relief - Children under 3 years old: Not recommended, except under a doctor's guidance - Children 12 years and older, and 3 to 11 years old: Consult a doctor for dosage recommendations Please consult a healthcare professional before taking aspirin or any other medication. Sources: [1] https://www.uptodate.com/contents/aspirin-uses-dosage-and-side-effects - This link takes you to a paid subscription content about Aspirin, however, it is accessible through a medical library. [2] https://www.heart.org/en/healthy-living/ask-the-doctors/do-you-recommend-low-dose-aspirin-for-heart-health [3] http://www.nlm.nih.gov/medlineplus/ency/article/001566.htm
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