Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the drug label provided by the FDA [3], the initial dose of Lipitor is usually 10-20 mg once daily, and the maximum recommended dose is 80 mg once daily. The dosage may be adjusted based on the patient's response to treatment and individual needs. It is recommended to monitor the patient's cholesterol levels regularly and adjust the dosage accordingly.

Medscape [2] states that Lipitor therapy is usually initiated with a low dose and then titrated up as needed. The goal is to achieve the target cholesterol level, which may vary depending on the patient's risk factors. For example, patients with a higher risk of cardiovascular disease may require a lower target cholesterol level. The decision to adjust the dosage should be based on the patient's response to treatment, potential side effects, and other factors such as drug interactions.

Drug Patent Watch [1] provides information on the patent status of Lipitor, but does not offer any guidance on when the dosage should be adjusted.

In summary, the dosage of Lipitor should be adjusted based on the patient's response to treatment and individual needs. The initial dose is usually 10-20 mg once daily, and the maximum recommended dose is 80 mg once daily. The decision to adjust the dosage should be based on the patient's response to treatment, potential side effects, and other factors such as drug interactions. It is recommended to monitor the patient's cholesterol levels regularly to achieve the target cholesterol level.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://reference.medscape.com/drug/lipitor-atorvaliq-atorvastatin-342446
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf