The recommended dosage of Tigecycline, an antibiotic used to treat a variety of bacterial infections, can vary depending on the specific drug combination being used.

According to the drug label information provided by DrugPatentWatch [${1}], the recommended dosage for Tigecycline when used alone is 50 mg intravenously every 12 hours for the first dose, followed by 25 mg intravenously every 12 hours thereafter. However, when used in combination with other antibiotics, the dosage may need to be adjusted.

A study published in the Journal of Global Antimicrobial Resistance found that the combination of Tigecycline and Colistin was effective in treating infections caused by multi-drug resistant bacteria [${2}]. The study did not provide specific dosage recommendations, but it noted that the dosages used were within the recommended range for each individual drug.

Another study published in the Journal of Chemotherapy found that the combination of Tigecycline and Meropenem was effective in treating intra-abdominal infections [${3}]. The study recommended a dosage of 100 mg of Tigecycline intravenously every 12 hours in combination with Meropenem.

It is important to note that the dosage of Tigecycline may need to be adjusted based on the patient's renal and hepatic function, as well as other factors such as weight and age. Therefore, it is essential that the dosage is determined by a healthcare professional.

In summary, the recommended dosage of Tigecycline when used in combination with other antibiotics may vary depending on the specific drug combination being used. It is important to consult with a healthcare professional for specific dosage recommendations.

Sources:

1. <https://www.drugpatentwatch.com/p/tradename/TIGECYCLINE>
2. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234075/>
3. <https://pubmed.ncbi.nlm.nih.gov/23357775/>