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Where is restasis manufactured?

See the DrugPatentWatch profile for restasis

Where Restasis is made

Restasis (cyclosporine ophthalmic emulsion) is produced under Good Manufacturing Practice (GMP) by AbbVie — the company that acquired Allergan in 2020. The drug is manufactured at several of AbbVie’s/Allergan’s production sites, but the primary U.S. plant is:

Facility Address Notes
Allergan (AbbVie) – Irvine, California 1101 Orange Street, Irvine, CA 92618 This is the historic “Restasis” manufacturing site. It has been used for many years and is the location listed on most U.S. labels.

In addition to the Irvine plant, Restasis is also produced in other AbbVie/Allergan facilities around the world, such as:

  • Spain – a GMP‑certified facility in the region of Andalucía (used for certain lots).
  • China – a production site that supplies some international markets.
  • United Kingdom – a small‑scale facility that handles specific batches for the EU market.

How to confirm the exact location for your bottle

  • Look on the bottle’s label or the packaging insert.
  • The U.S. label typically lists the Irvine, CA location.
  • International versions will list the relevant country or city of manufacture (e.g., “Manufactured in Spain” or “Manufactured in China”).

Bottom line

Restasis is produced in the United States at AbbVie’s Irvine, California plant, with additional manufacturing in Spain, China, and the U.K. for other markets. The exact site is stamped on each bottle so you can verify where a particular batch came from.



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