Lipitor is a medication used to lower cholesterol levels in the body. As with any medication, there are potential interactions with natural supplements. The sources provided give insight into which supplements may interact with Lipitor.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and natural supplements. However, this does not mean that interactions cannot occur.

SingleCare [2] states that certain supplements, such as St. John's Wort, can decrease the effectiveness of Lipitor. This is because St. John's Wort can increase the breakdown of the medication in the liver, making it less effective. Additionally, grapefruit and grapefruit juice can increase the concentration of Lipitor in the blood, potentially leading to side effects.

Mayo Clinic [3] provides a list of supplements that may interact with statins, the class of medication that Lipitor belongs to. These supplements include red yeast rice, which contains a compound that is similar to the active ingredient in statins, and can increase the risk of side effects. Other supplements to be cautious of include coenzyme Q10, guggul, and niacin.

It is important to talk to a healthcare provider before taking any natural supplements while on Lipitor. They can provide guidance on which supplements are safe to take and which should be avoided. Additionally, it is important to disclose all medications and supplements being taken to avoid potential interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.mayoclinic.org/healthy-lifestyle/consumer-health/in-depth/herbal-supplements/art-20046488