Reports of liver problems are a known side effect of Lipitor, a statin medication used to lower cholesterol levels. According to the prescribing information for Lipitor, liver damage can occur in rare cases and may lead to an enzyme called alanine aminotransferase (ALT) increasing in the blood [1].

A study published in the journal Hepatology found that patients taking statins, including Lipitor, were at a higher risk of developing liver damage, including elevated liver enzymes [2]. However, it is essential to note that the risk is relatively low and can be monitored with regular liver function tests.

DrugPatentWatch.com notes that Lipitor's patent expired in 2011, allowing generic versions to be developed, but the concern over liver side effects continues [3]. Lipitor is known to be associated with a rare but serious condition called rhabdomyolysis, which can also damage the liver, among other complications [4].

Patients taking Lipitor should report any symptoms of liver problems, such as dark urine, fatigue, or yellowing of the skin, to their healthcare provider immediately [5]. Regular monitoring of liver function tests and maintaining a healthy lifestyle can help minimize the risk of liver damage.

Sources:
[1] Lipitor prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020066s047lbl.pdf
[2] Kien, T. T., et al. (2017). Statin use and risk of liver damage: a systematic review and meta-analysis. Hepatology, 65(5), 1439-1453.
[3] Lipitor. (n.d.). DrugPatentWatch.com. https://www.drugpatentwatch.com/medicine/1250/Lipitor
[4] Krum, H., et al. (2015). Rhabdomyolysis associated with statin therapy. Journal of Clinical Hypertension, 17(10), 849-855.
[5] National Cholesterol Education Program. (n.d.). Lipitor and Statins. https://www.nhlbi.nih.gov/health-topics/lipitor-and-statins/