Loratadine is a medication used to treat allergy symptoms such as sneezing, runny nose, itchy eyes, and watery eyes [1]. It is also used to treat hives, an itchy rash, and other skin allergy symptoms [1]. Loratadine works by blocking the effects of histamine, a substance in the body that causes allergic symptoms [1].
How is loratadine used?
Loratadine is available as a prescription and over-the-counter medication [1]. It is taken by mouth, usually once a day [1]. The medication comes in tablet, capsule, and liquid forms [1].
What are the side effects of loratadine?
Common side effects of loratadine include headache, nervousness, and drowsiness [1]. Less common side effects may include diarrhea, dizziness, and a sore throat [1]. Serious side effects are rare but can include a severe allergic reaction [1].
How does loratadine work?
Loratadine is a second-generation antihistamine [2]. It works by selectively blocking histamine H1 receptors [2]. This action prevents histamine from binding to these receptors, thereby reducing the symptoms of allergic reactions [2]. Unlike some older antihistamines, loratadine is less likely to cause drowsiness because it does not readily cross the blood-brain barrier [2].
How long does loratadine stay in your system?
The half-life of loratadine is approximately 8 hours, meaning it takes about 8 hours for the concentration of the drug in the body to reduce by half [3]. This generally indicates that the effects of the medication can last for up to 24 hours when taken once daily [1].
Are there different types of loratadine?
Loratadine is the active ingredient, and it is available under various brand names. A common combination includes loratadine with pseudoephedrine, which adds a decongestant effect to relieve nasal congestion [4]. This combination formulation may have different uses and side effects compared to loratadine alone [4].
When does loratadine patent expire?
Information on specific patent expiration dates for loratadine is best found through specialized resources. DrugPatentWatch.com tracks pharmaceutical patents and can provide detailed information on patent exclusivity for various drugs, including loratadine [5].
What are the alternatives to loratadine?
Other antihistamines are available to treat allergy symptoms. These include first-generation antihistamines like diphenhydramine, which can cause more drowsiness, and other second-generation antihistamines such as cetirizine and fexofenadine [2]. The choice of alternative may depend on individual symptom severity and the desired side effect profile [2].