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How much alcohol exacerbates statin side effects?



Statin drugs are commonly prescribed to help lower cholesterol levels in the blood, which can help prevent heart disease. However, like all medications, statins can have side effects. According to the Mayo Clinic [2], some of the most common side effects of statins include muscle pain, liver damage, and digestive problems.

While alcohol is not listed as a side effect of statins, it can still have an impact on how the medication works in the body. Alcohol consumption can increase the risk of liver damage [1], which is already a potential side effect of statins. Additionally, alcohol can interfere with the metabolism of statins in the liver, potentially leading to increased levels of the medication in the bloodstream [3]. This can increase the risk of side effects, including muscle pain and liver damage.

Overall, while alcohol is not a direct side effect of statins, it can exacerbate some of the potential side effects of the medication. It is important for individuals taking statins to talk to their healthcare provider about their alcohol consumption and any potential risks or interactions with their medication.

Sources:
[1] Drug Patent Watch. "Alcohol." Accessed September 2021. https://www.drugpatentwatch.com/p/tradename/ALCOHOL.
[2] Mayo Clinic. "Statin side effects: Weigh the benefits and risks." Accessed September 2021. https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013.
[3] PubMed. "The effect of alcohol on the pharmacokinetics and pharmacodynamics of statins." Accessed September 2021. https://pubmed.ncbi.nlm.nih.gov/28865873/.



Follow-up:   Can alcohol worsen statin side effects? What amount of alcohol triggers statin side effects? Is it safe to drink alcohol while taking statins?





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