Ticagrelor 180 mg?

Ticagrelor 180 mg is the loading dose used in acute coronary syndrome (ACS) management. Here’s how it fits into the dosing:

- Loading dose: 180 mg total, given as two 90 mg tablets taken together (with low-dose aspirin, about 75–100 mg daily).
- Maintenance: after the loading dose, 90 mg twice daily (BID) for up to 12 months.
- Long-term option: in some patients, after 12 months, 60 mg BID may be used to reduce bleeding risk, especially for prior MI patients who continue therapy (as in the PEGASUS program).

Important notes:
- 180 mg is not a single tablet; it’s administered as two 90 mg tablets at once.
- Indications: used for ACS (STEMI/NSTEMI, and others) to reduce risk of cardiovascular death, MI, or stroke, in combination with aspirin.
- Do not use if you have active major bleeding or a history of intracranial hemorrhage. Use with caution in liver disease and in people at high risk of bleeding.
- Common side effects: bleeding (including serious bleeding), dyspnea, headache, dizziness, and nausea.
- Interactions: strong CYP3A4 inhibitors or inducers can affect ticagrelor levels; avoid certain drug combinations and monitor bleeding risk with NSAIDs or other antiplatelets.

If you’re asking about a specific prescription or have a patient case, tell me more and I can tailor the info (e.g., who’s taking it, any other meds, kidney/liver status). Also, always follow your clinician’s exact dosing instructions.