Mannitol is available under several brand names, including Arginine [1].
What are other uses for mannitol?
Mannitol is primarily used as an osmotic diuretic. It works by increasing the osmolarity of the blood, which draws water out of the tissues, including the brain and eyes, and into the bloodstream. This reduction in fluid volume can lower pressure within the skull and eyes. It is also used to help remove excess fluid from the body in certain patients [2].
How is mannitol administered?
Mannitol is typically administered intravenously as an infusion [1]. The dosage and rate of administration depend on the patient's condition and response.
What are the potential side effects of mannitol?
Common side effects associated with mannitol infusion can include headache, nausea, vomiting, dizziness, and changes in fluid and electrolyte balance. More serious side effects can occur, such as kidney problems, allergic reactions, and changes in blood pressure [2]. Patients receiving mannitol are closely monitored for these potential reactions.
When does mannitol's patent protection expire?
Information regarding specific patent expiry dates for mannitol is not readily available, as it is a well-established medication. Patent exclusivity for older drugs often expires long before generic versions become widely available, or the original patents may have expired years ago. DrugPatentWatch.com tracks patent information for many pharmaceuticals [3].