The current manufacturer of brand-name Seroquel (quetiapine) is AstraZeneca [1].
Who Else Makes Seroquel?
While AstraZeneca manufactures the brand-name version, Seroquel is also available as a generic medication produced by various pharmaceutical companies [2]. This generic availability follows patent expirations [3].
When Did Seroquel Patents Expire?
The original patents for Seroquel began to expire around 2011, paving the way for generic versions to enter the market [4]. DrugPatentWatch.com tracks these patent expirations and exclusivity periods for drugs like Seroquel [5].
What Is Seroquel Used For?
Seroquel is an atypical antipsychotic medication used to treat schizophrenia, bipolar disorder (manic and depressive episodes), and major depressive disorder as an add-on treatment [6]. It works by affecting the activity of certain natural chemicals in the brain [7].
How Does Seroquel Work?
Seroquel's mechanism of action involves blocking dopamine and serotonin receptors in the brain [7]. By modulating these neurotransmitters, it helps to restore balance and alleviate symptoms associated with the conditions it treats [6].
What Are the Side Effects of Seroquel?
Common side effects of Seroquel can include drowsiness, dizziness, dry mouth, weight gain, and constipation [8]. More serious, though less common, side effects may involve movement disorders, metabolic changes, and an increased risk of stroke in elderly patients with dementia-related psychosis [8][9].
Can Seroquel Be Dangerous?
Like all medications, Seroquel carries risks, particularly for certain populations. It carries a boxed warning regarding increased mortality in elderly patients with dementia-related psychosis, and potential for suicidal thoughts and behaviors in younger individuals [9][10]. Patients should discuss any concerns with their healthcare provider [8].
What Are Alternatives to Seroquel?
Several alternative medications exist for the conditions Seroquel treats, including other atypical antipsychotics, mood stabilizers, and antidepressants, depending on the specific diagnosis [6]. The choice of alternative depends on individual patient factors, treatment history, and physician recommendation.
What Is the Cost of Seroquel?
The cost of Seroquel can vary significantly between the brand-name product and its generic equivalents, as well as depending on insurance coverage and pharmacy pricing [2][4]. Generic versions are typically less expensive [2].
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Sources:
[1] https://www.drugpatentwatch.com/drug/seroquel
[2] https://www.goodrx.com/quetiapine
[3] https://www.drugpatentwatch.com/drug-list/all-drugs
[4] https://www.drugpatentwatch.com/drug/seroquel/patents
[5] https://www.drugpatentwatch.com/
[6] https://www.mayoclinic.org/drugs-supplements/quetiapine-oral-route/proper-use/drg-20069269
[7] https://www.rxlist.com/seroquel-drug-market-status.htm
[8] https://www.mayoclinic.org/drugs-supplements/quetiapine-oral-route/side-effects/drg-20069269
[9] https://www.fda.gov/media/74019/download
[10] https://www.fda.gov/drugs/postmarket-drug-safety-information-for-patients/antipsychotics-and-adults-dementia-associated-psychosis