Does Cosentyx (secukinumab) cause tiredness or fatigue?
Cosentyx’s prescribing information and patient-relevant safety information include fatigue/tiredness as a possible side effect. If you notice new or worsening tiredness after starting Cosentyx, it’s worth telling your clinician, especially if it’s persistent or severe.
How common is fatigue with Cosentyx?
Fatigue can occur in people taking biologics like Cosentyx, but the exact frequency can vary by source and by what was reported in clinical studies and post-marketing experience. If you’re comparing alternatives or deciding whether to continue, your prescriber can help interpret how likely it is for your situation.
What else could be causing tiredness while you’re on Cosentyx?
Tiredness in people treated for psoriasis, psoriatic arthritis, or ankylosing spondylitis can also come from:
- Your underlying inflammatory condition (which can improve on treatment but not always immediately).
- Intercurrent infections (including respiratory infections), since biologics can increase infection risk.
- Other medications you take (pain meds, steroids, antidepressants, antihistamines, etc.).
Because the cause matters, clinicians typically ask when the fatigue started, whether you also have fever or infection symptoms, and how it changed after each dose.
When should you seek medical help urgently?
Get urgent medical care if tiredness comes with signs of a serious problem, such as:
- Fever, chills, or symptoms of infection
- Shortness of breath, chest pain, fainting
- Severe weakness or dizziness
- Any signs of an allergic reaction (swelling of face/lips, trouble breathing, widespread rash)
What can you do if you’re feeling tired on Cosentyx?
Don’t stop Cosentyx on your own. Contact your clinician to discuss:
- Whether your fatigue lines up with starting or dose changes
- Whether you should be evaluated for infection or other causes
- Whether your dosing schedule or supportive care should change
If you want, tell me what condition you’re taking Cosentyx for (psoriasis, psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis), when the tiredness started relative to your first dose, and whether you have any infection symptoms. I can help you think through the most likely causes and what questions to bring to your doctor.