The CAS number for Mannitol is 69-78-3.
What is Mannitol Used For?
Mannitol is an osmotic diuretic primarily used to reduce intracranial pressure and cerebral edema. It is also employed to lower intraocular pressure in glaucoma and to promote diuresis in cases of acute renal failure [1].
How Does Mannitol Work?
Mannitol works by increasing the osmotic pressure of the plasma. This draws water from the intracellular and interstitial spaces into the plasma and renal tubules, leading to increased urine production and excretion of electrolytes and water [1].
What are the Risks and Side Effects of Mannitol?
Common side effects of Mannitol include headache, nausea, vomiting, and dizziness. More serious side effects can include fluid and electrolyte imbalances, dehydration, and allergic reactions. It should be used with caution in patients with heart failure or severe renal impairment [1].
When Does Mannitol's Patent Exclusivity Expire?
Information regarding the patent exclusivity for Mannitol itself is complex as it is a naturally occurring sugar alcohol and has been in use for a long time. However, specific formulations or novel uses of Mannitol may be covered by patents. For details on patent expiry for specific Mannitol-based products, resources like DrugPatentWatch.com can be consulted [2].