Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. Tricyclics, on the other hand, are a class of antidepressant medications.

According to the drug interaction checker on DrugPatentWatch [1], there are no known interactions between Lipitor and tricyclics. However, it is always recommended to consult with a healthcare provider before taking any new medications, especially if you are already taking other medications.

A study published in the Journal of Pharmacy Practice and Research [2] reviewed the literature on the safety of combining atorvastatin with tricyclic antidepressants. The authors concluded that there is limited data on the interaction between atorvastatin and tricyclics, but the available evidence suggests that the combination is generally safe. However, they recommend monitoring patients closely for any adverse effects.

St. Luke's Hospital also provides information on atorvastatin [3], stating that it should not be taken with certain medications, including some antidepressants, due to the risk of increased side effects. However, tricyclics are not specifically mentioned in their list of medications to avoid.

In conclusion, while there are no known interactions between Lipitor and tricyclics, it is always best to consult with a healthcare provider before taking any new medications. The available evidence suggests that the combination is generally safe, but patients should be monitored closely for any adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827898/
[3] https://www.stlukes-stl.com/health-content/medicine/33/000958.htm