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Clindamycin phosphate gel ingredients?

See the DrugPatentWatch profile for Clindamycin

Below is a typical ingredient list for a 1.2 % clindamycin phosphate topical gel (the formulation most commonly sold for acne treatment). Note that the exact wording and the presence of certain additives can vary slightly from one manufacturer to another, so you should check the product’s own label or the manufacturer’s website for the exact version you have in hand.

Active Common Inactive (Vehicle) Ingredients Other Typical Additives
Clindamycin phosphate 1.2 % w/w Water (solvent) 1,2‑Hexanediol (preservative/solvent)
Carbomer (gelling agent) Polysorbate 80 (emulsifier)
Glycerin (humectant) Methylparaben (preservative – some formulations use it; others are preservative‑free)
Sodium hydroxide (pH adjuster) Propylparaben (preservative – optional)
Phenoxyethanol (preservative – optional)
Ethylparaben (preservative – optional)
Poloxamer 407 (stabilizer – optional)
Triethanolamine (neutralizer/viscosity control – optional)

What you’ll usually find on the bottle or in the packaging:

  1. Active ingredient: Clindamycin phosphate (1.2 % w/w)
  2. Water (aqua) – the solvent base.
  3. Carbomer – a polymer that gives the gel its viscosity.
  4. Glycerin – a humectant that keeps the gel from drying out.
  5. Polysorbate 80 (or another polysorbate) – helps the gel stay smooth and prevents separation.
  6. 1,2‑Hexanediol – a solvent/preservative that also improves spreadability.
  7. Sodium hydroxide – adjusts the pH to make the gel skin‑friendly (usually around pH 5‑6).
  8. Preservatives – depending on the brand, you may see methylparaben, propylparaben, phenoxyethanol, or no preservative at all if the formulation is “preservative‑free.”

Things to keep in mind

  • Allergens & sensitivities – If you have a known allergy to any of the common excipients (e.g., parabens, phenoxyethanol, or glycerin), check the product’s ingredient list carefully.
  • Preservative‑free options – Some newer formulations (e.g., certain “organic” or “natural” brands) omit parabens and phenoxyethanol.
  • Packaging – A clear or lightly tinted tube is standard; the bottle will list all ingredients under a heading such as “Inactive ingredients.”

If you’d like the exact ingredient list for a particular brand (for example, “Clindacin® 1.2 % Gel” or “Clindamycin Phosphate 1.2 % Gel” from a specific manufacturer), let me know the brand name or product code and I can provide a more precise breakdown.



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